VARIABILITY IN INTRAMURAL GANGLIA AND EFFERENT NEURONS ALONG THE DIFFERENT ROUTES OF THE BILE
Keywords:
biliary system, gallbladder, extrahepatic bile ducts, intramural ganglia, efferent neurocytes.Abstract
The gallbladder ganglia are sites of complex modulatory interactions that ultimately affect the function of muscle and epithelial cells in the organ. This study aimed to identify the morphological features of intramural ganglia and efferent neurons in the gallbladder and extrahepatic biliary tract. Neurohistological methods, including silver nitrate impregnation according to the Bilshovsky-Gros method and Campos, were used to morphometrically study the intramural nervous apparatus of the gallbladder wall, common bile duct, and hepatic ducts in 12 dogs, 6 of which underwent right-sided cervical vagotomy.
The results showed that the largest nerve ganglia are located in the wall of the gallbladder, particularly in the neck of the bladder, and the common bile duct. In contrast, the walls of the hepatic ducts contain small microganglia and single neurocytes. The intramural nervous apparatus of the gallbladder and extrahepatic bile ducts demonstrated pronounced polymorphism in the shape of the bodies of efferent neurons.
