ENDOCRINE CELLS OF THE COLON EPITHELIA AS PART OF THE DIFFUSE ENDOCRINE SYSTEM

Abstract

One of the cytogenetic options for divergent differentiation of cells of the cambial reserve of intestinal epithelial tissue is the so-called. entero- and colonoendocrinocytes. They produce biologically active substances that maintain homeostasis and regulate the functioning of the gastrointestinal tract. Being the functionally leading tissue of the entire gastrointestinal tract, all types of epithelial cells, and enteroendocrine cells, in particular, are involved in the pathomorphogenesis of intestinal diseases. Dysfunction of these cells leads to disturbances in microcirculation and regeneration, which and/or contributes to the development of inflammatory diseases, or is an important part of their pathomorphogenesis.