PATHOMORPHOLOGICAL PICTURE OF CHANGES IN THE SUPERFICIAL VEINS OF THE POPLITEAL REGION.
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Key words: varicose veins, plasmatic swelling, elastolysis, venostasis.##article.abstract##
Abstract. Varicose veins are the most common vascular disease in humans. Veins
have valves that help the blood return gradually to the heart without leaking blood.
When these valves become weak, blood and fluid collect and pool by pressing against
the walls of the veins, causing varicose veins. In the cardiovascular system, mechanical
forces are important determinants of vascular homeostasis and pathological processes.
Blood vessels are constantly exposed to a variety of hemodynamic forces, including
shear stress and environmental strains caused by the blood flow. In varicose veins
within the leg, venous blood pressure rises in the vein of the lower extremities due to
prolonged standing, creating a peripheral tension in the vessel wall thereby causing
mechanical stimulation of endothelial cells and vascular smooth muscle.
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